Estra-4,9-diene-3,17-dione
Product Name: Estra-4,9-diene-3,17-dione
CAS NO.: 5173-46-6
Appearance: White or almost white crystalline powder
Purity: ≥98.0%
Products Description
Product Name: Estra-4,9-diene-3,17-dione
CAS NO.: 5173-46-6
Structural formula: 
Molecular formula: C18H22O2
Molecular weight: about 270.366
Density: 1.16 g/cm3
Boiling point: 466.5℃
Appearance: White or almost white crystalline powder
Purity: ≥98.0%
Melting point: 135℃
LOD: ≤0.50%
Package: Net 25 kg/Drum
Identification: Consistent with the main peak retention time of the standard solution
Usage: Intermediate of steroid hormone drugs
Note: Dienedione is strictly restricted for use in humans and is primarily used for research and synthesis of mesothelioma. Use in athletes may result in positive doping tests.
Storage conditions: It should be stored in a cool, dry, sunny, and well-ventilated place, avoiding direct sunlight and high temperatures.
Products feature
Thermal stability
Estra-4,9-diene-3,17-dione has a boiling point of 466.5℃ and a melting point of 135℃. It is not easy to decompose or isomerize under high-temperature hydrogenation or catalytic reaction conditions.
High reactivity
Compared with traditional Androst-4-ene-3,17-dione, this drug introduces a 4,9-diene bond in its molecular structure, making it easier to selectively add or acylate in subsequent reactions, shortening the synthesis process and reducing reagent consumption.
Strong versatility
Estra-4,9-diene-3,17-dione is an intermediate node in multiple synthetic routes and can be used as a key precursor in the synthesis of progestins, antiprogestins, and even some anti-tumor drugs.
FAQ
Q: Is Estra-4,9-diene-3,17-dione a steroidal compound?
A: Yes, Estra-4,9-diene-3,17-dione is a steroidal compound, specifically a precursor or analog of androgens and progestogens.
Q: What role does Estra-4,9-diene-3,17-dione play in synthesizing other drugs?
A: In drug synthesis, Estra-4,9-diene-3,17-dione typically serves as a starting material or intermediate, undergoing chemical reactions to convert into drug molecules with specific pharmacological activities. It can be further processed into various sex hormones and related drugs for treating or regulating hormone balance in the human body.
Q: Does Estra-4,9-diene-3,17-dione have biological activity in the human body?
A: While Estra-4,9-diene-3,17-dione may not have directly significant biological activity in the human body, it is an important precursor for synthesizing biologically active compounds. Once converted into other forms of steroid hormones, they can play important physiological and pharmacological roles in the human body.
Q: What safety precautions should be taken when handling or storing Estra-4,9-diene-3,17-dione?
A: When handling or storing Estra-4,9-diene-3,17-dione, appropriate safety measures should be followed, including wearing suitable personal protective equipment (such as gloves, safety goggles, and respiratory protection) and ensuring operations are conducted in a well-ventilated environment. Additionally, it should be stored in a dry, cool, dark place, away from heat and flammable materials.
Q: What is the primary use of Estra-4,9-diene-3,17-dione?
A: Estra-4,9-diene-3,17-dione is primarily used as a pharmaceutical intermediate in the manufacturing of various medications. Its specific applications in the pharmaceutical industry depend on the further chemical transformations and synthetic pathways it undergoes.
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